Figure 8
Membrane binding and stacking by P2 in silico and in vivo. (a) The end point (after 1.5 µs) of the CG MD simulation. The lower bilayer represents the pre-formed membrane, while the upper bilayer was formed during the simulation. (b) Mapping of contacts during the simulation. The most important polar contacts are indicated in magenta and the major nonpolar contacts are indicated in green. Further polar contacts are indicated in orange. Details are shown in Supplementary Fig. S1. (c) Formation of membrane domains by wild-type (left) and L27D mutant (right) P2 in cell culture. The scale bar is 10 µm in length. |