Figure 3
Metal ion-binding sites identified for HaAP. (a) Zn2+-binding sites (M1 and M2) and Mg2+-binding sites (M3) around the active site. (b) Mg2+-binding sites (M4) at the monomer–monomer interface. Chain A and chain B are coloured cyan and grey, respectively. (c) Mg2+-binding sites (M5) at the surface of a single chain. The mesh shows the Fo − Fc OMIT map within a +3σ contour level. Zn2+, Mg2+, Cl− and the O atom of water are shown by spheres coloured black, orange, green and red, respectively. |