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Figure 6
Domain displacement in aIF2γ during transition from the active to the inactive state. The G domains of the S2 and S3 structures are superimposed. Domains are numbered with roman numerals and shown in dark and light grey for the OFF and ON states, respectively. In the OFF state, switch 2 and loop 334–353 are shown in orange. The same elements in the ON state are shown in blue. Upon transition from the OFF state to the ON state, domains II and III rotate about an axis approximately coincident with a line connecting the Cα atoms of residues 292–293 (magenta spheres) approaching domain G.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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