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Figure 2
Comparing the PQ dimer with the AC dimer derived from BGLPf-WT. Sub­units A and C derived from BGLPf-WT are shown in cyan and orange, respectively, and subunits P and Q derived from BGLPf-M3 are shown in red and green, respectively. The PQ dimer is superimposed on the AC dimer. The P–­Q dimeric interface is similar to the AC interface. The Arg381 and Tyr382 side chains contribute to both the PQ and AC interactions, whereas the Arg448 and Glu449 side chains do not contribute to the PQ or AC inter­actions (b) (stereo diagram). The side chain of Arg471 only contributes to the AC interaction (c) (stereo diagram) and corresponds to interactions AC-5 and AC-6 in Table 2[link](a). This side-chain interaction of Arg471 is a remarkable difference between the PQ and AC dimers. (b) is in the same orientation as (a). (b) was rotated 120° around the horizontal axis to generate (c).

Journal logoBIOLOGICAL
ISSN: 1399-0047
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