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Figure 4
Superposition of the SGSH backbone on those of five related sulfatases: SGSH (red), ASA (orange), ASB (yellow), PAS (blue), GALNS (green) and BcPMH (brown). SGSH shares a common fold with O-sulfatases consisting of a large central β-sheet with decorating helices (`conserved region', top); the loops form a more variable region (`nonconserved region', bottom). For orientation, the SGSH N-terminus and C-terminus are shown (N and C, respectively), as are some secondary-structure elements (as in Fig. 2[link]a) and some atoms in the active site in ball representation: Ca2+ (dark grey), phosphate O atoms (orange), FGly Cβ (light grey) and free hydroxyl O atom (red).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 70| Part 5| May 2014| Pages 1321-1335
https://doi.org/10.1107/S1399004714002739
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