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Figure 1
Inhibition of bacterial sialidase by diplacone. (a) Time-dependent inhibition of Cp-NanI in the presence of diplacone with varying pre-incubation times. (b) Pre-incubation time dependence of the fractional velocity of the enzyme-catalyzed reaction in the presence of varying concentrations of diplacone. (c) Dependence of kobs on the concentration of dipacone. The kobs values determined in (b) were fitted to equation (2) in Supplementary Fig. S3(a). (d) Time course of slow-binding inhibition by diplacone.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 70| Part 5| May 2014| Pages 1357-1365
https://doi.org/10.1107/S1399004714002971
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