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Figure 5
General overview of mC5a and mC5a-desArg structures. (a) Elution profile of recombinant mC5a (purple) and mC5a-desArg (orange) on the SOURCE 15S column. (b) Overall structure of mouse C5a at 1.4 Å resolution. The four α-helices are labelled according to the hC5a nomenclature and the three internal disulfide bridges stabilizing the four-helix bundle are highlighted in yellow. (c) Final model and electron-density maps for the mC5a structure. The 2mFoDFc map is shown as a blue mesh and contoured at 1σ. The mFoDFc map is show in blue/green and contoured at 3σ. (d) As in (c) but for the mC5a-desArg structure.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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