Figure 2
Crystal structures of BurrH and the BurrH–DNA complex. (a) Crystal structures of apo and DNA-bound BurrH (2.21 and 2.65 Å resolution, respectively). Cartoon representation of the crystal structures perpendicular to the longitudinal DNA axis (left panel) and along the DNA helix (right panel). The helical elements of BurrH are shown as cylinders and the duplex oligonucleotide is represented in stick mode. (b) Ribbon diagram of a BuD repeat. The side chains of the key residues (Supplementary Fig. S2) are shown in stick mode, including their positions in the repeat. Hydrophobic amino acids (Phe, Ile, Val and Leu) are coloured light blue, Gln magenta, Lys orange and the invariant Asn green. |