Structural insights into the human RyR2 N-terminal region involved in cardiac arrhythmias

Borko, Ľ.; Bauerová-Hlinková, V.; Hostinová, E.; Gašperík, J.; Beck, K.; Lai, F.A.; Zahradníková, A.; Ševčík, J.

doi:10.1107/S1399004714020343

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 3
Alignment of N-terminal RyR regions. (a) hRyR2^1–606 and oRyR1^1–559, (b) hRyR2^1–606 and mRyR2^1–547. Identical amino acids are in bold. Secondary-structure elements determined from the X-ray structures are shown as arrows (β-strands) and helices. Blue, green and red colours indicate the residues that are missing in 4jkq, 4l4h and 2xoa, respectively. Missing side chains are boxed.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 70| Part 11| November 2014| Pages 2897-2912

https://doi.org/10.1107/S1399004714020343

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