Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control

Chitnumsub, P.; Jaruwat, A.; Riangrungroj, P.; Ittarat, W.; Noytanom, K.; Oonanant, W.; Vanichthanankul, J.; Chuankhayan, P.; Maenpuen, S.; Chen, C.-J.; Chaiyen, P.; Yuthavong, Y.; Leartsakulpanich, U.

doi:10.1107/S1399004714023128

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 2
Amino-acid binding pocket of PvSHMT. (a) D-Ser in the ternary complex PvSHMT–D-Ser–5FTHF with the PLP–D-Ser (PLD) Schiff base and (6R)-5FTHF coloured in magenta in protomer A (pink) and protomer B (blue) with a glycerol (GOL) molecule in green. (b) L-Ser in the binary complex PvSHMT–L-Ser with a PLP–L-Ser (PLS) Schiff base. (c) Superposition of the two complexes showing the configurations of D-Ser and L-Ser.

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 70| Part 12| November 2014| Pages 3177-3186

doi:10.1107/S1399004714023128

Follow Acta Cryst. D

Search term		doi		Advanced search
Author		volume	page