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Figure 10
Effect of overfitting on FSC curves. (a) A refined structure that does not display the hallmarks of overfitting. FSCwork is shown with a continuous blue line and FSCtest with a dashed red line. The resolution cutoff applied during refinement is shown as a vertical dashed line. (b) An overfitted structure showing disagreement between FSCwork and FSCtest and a sharp decrease at the resolution limit applied during refinement.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
Volume 71| Part 1| January 2015| Pages 136-153
doi:10.1107/S1399004714021683
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