Figure 3
Integrated structural biology approach combining correlative light microscopy, soft X-ray cryo-microscopy and electron cryo-microscopy with high-resolution structure information, thus enabling the dissection of dynamic processes at different levels of resolution and complexity. The biological process is visualized by light microscopy (LM), transmission X-ray cryo-microscopy (cryo-TXM), electron cryo-tomography (cryo-ET), single-particle cryo-EM and/or macromolecular crystallography (MX). Adapted from Zeev-Ben-Mordehai et al. (2014). |