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Figure 1
Detecting nonlinearity in Guinier plots. A typical example of a Guinier plot for Guinier region 1 is shown. Data points are plotted as gray circles. The linear fit through each set of three data points is plotted with alternating solid gray and dashed black lines for clarity. A plot of the slope of each fit is shown in the inset. The set of slopes is fitted with a linear regression, shown by the solid black line. Guinier regions that are linear will show a flat line with no dependence on q2. Guinier regions that are nonlinear will exhibit a dependence on q2, detected using the t-­statistic described in the text. This process is performed for each of the three Guinier regions.

Journal logoBIOLOGICAL
ISSN: 1399-0047
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