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 | STRUCTURAL BIOLOGY |
accessStructural basis of sialidase in complex with geranylated as potent natural inhibitors. Corrigendum
aSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Buk-gu, Gwangju 500-712, Republic of Korea, bSteitz Center for Structural Biology, Gwangju Institute of Science and Technology (GIST), Buk-gu, Gwangju 500-712, Republic of Korea, cDepartment of Chemistry, Gwangju Institute of Science and Technology (GIST), Buk-gu, Gwangju 500-712, Republic of Korea, dInfection Control Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 580-185, Republic of Korea, and eDivision of Applied Life Science (BK21 Program, IALS), Graduate School of Gyeongsang National University, Jinju 660-701, Republic of Korea
*Correspondence e-mail: khpark@gnu.ac.kr, eom@gist.ac.kr
A correction is made to the article by Lee et al. [(2014) Acta Cryst. D70, 1357–1365].
Keywords: sialidase; NanI; geranylated flavonoid; diplacone; sialidase inhibitor; corrigendum.
The authors of Lee et al. (2014![[Lee, Y., Ryu, Y. B., Youn, H.-S., Cho, J. K., Kim, Y. M., Park, J.-Y., Lee, W. S., Park, K. H. & Eom, S. H. (2014). Acta Cryst. D70, 1357-1365.]](../../../../../../logos/arrows/d_arr.gif "Lee, Y., Ryu, Y. B., Youn, H.-S., Cho, J. K., Kim, Y. M., Park, J.-Y., Lee, W. S., Park, K. H. & Eom, S. H. (2014). Acta Cryst. D70, 1357-1365.")
) have made a careful re-analysis of all of data sets used in their of the putative complex between the human pathogen Clostridum perfringens sialidase and the natural inhibitory compound, geranylated flavonoid diplacone, described in the article. They now no longer believe that their structure (PDB accession number: 4l2e) is supported by X-ray diffraction data and thus have asked for the 4l2e entry to be made obsolete in the Protein Data Bank. This does not affect the validity of the biochemical characterization of specific interactions of the sialidase with diplacone and other naturally occurring compounds reported in the paper.
References
Lee, Y., Ryu, Y. B., Youn, H.-S., Cho, J. K., Kim, Y. M., Park, J.-Y., Lee, W. S., Park, K. H. & Eom, S. H. (2014). Acta Cryst. D70, 1357–1365. CrossRef IUCr Journals Google Scholar
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