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![[Figure 1]](dw5123fig1mag.jpg)
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Figure 1
Overview of cation-binding sites in E. coli GyrB43. (a) Cartoon of the K-only model of the GyrB43 homodimer with an enlarged inset showing the relative positions of the metal-binding sites and the bound ADPNP (abbreviated to ANP). The slate grey and pale yellow colours define the two subunits, whilst the additional colours in the inset indicate the regions that participate in cation binding as shown in (b). These images are also reproduced as stereoviews in Supplementary Fig. S1. (b) Schematic showing details of sites 1 and 2 and the Mg-ATP binding site. The colours of the protein backbone correspond to the colours used in the inset in (a). Where possible the approximate spatial arrangement of the various structural elements has been preserved, with the exception of the motif bearing Arg22, which has been moved to the lower left-hand corner to aid clarity. H atoms have been omitted. Circles labelled `W' indicate water molecules. |
![[Figure 1]](dw5123fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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