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![[Figure 1]](kw5120fig1mag.jpg)
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Figure 1
Crystal structures of the FnIII-3 and FnIII-4 domains of integrin β4. (a) Diagram of the domain structure of the α6β4 cytoplasmic region. (b, c) Orthogonal views of ribbon representations of the crystal structures of the FnIII-3 (b) and FnIII-4 (c) domains. (d, e) Stereoviews of 2mFobs − DFcalc simulated-annealing OMIT maps (contoured at 1σ) of representative regions of FnIII-3 (d) and FnIII-4 (e) superimposed on the refined models. For FnIII-3, an anomalous difference map (contoured at 4σ) is shown in magenta. Phases were calculated from models in which the residues and the water molecules shown were removed and the B factors were reset to the Wilson-plot value; the models were then refined by simulated annealing (start temperature 4000 K). |
![[Figure 1]](kw5120fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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