Figure 10
(a) ANS molecules within the differently shaped cavities (shown in van der Waals mesh representation) of the present Hyp-1 chain L (green), 1txc (yellow) and 4a80 (red). All the available sites are probed by the ligand only in the Hyp-1 complex. (b) Structural alignment of these protein chains (colour coded as in a), with highlighting of residues involved in ANS contacts (<3.2 Å). |