Figure 4
The coenzyme A groups of monomers B (a, d, g), D (b, e, h) and F (c, f, i) depicted in ball-and-stick representation (with atoms colour-coded as follows: carbon, green; oxygen, red; phosphorus, magenta; nitrogen, blue; sulfur, yellow) fitted into (top row) Fo − Fc difference Fourier OMIT maps (green mesh; contour level 3.0σ, calculated without the substrate), (middle row) 2Fo − Fc difference Fourier maps (blue mesh; contour level 1.0σ) calculated with PHENIX (Adams et al., 2010) and (bottom row) 2Fo − Fc difference Fourier maps (blue mesh; contour level 2.0σ) using the `feature-enhanced' option of PHENIX (Adams et al., 2010; Pražnikar et al., 2009; Afonine et al., 2015). |