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![[Figure 7]](tz5079fig7mag.jpg)
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Figure 7
Actin-binding C-domain of ABP34. (a) Multiple sequence alignment of the strong actin-binding region (216–244) in the C-domain of ABP34 with the actin-binding regions in α-actinin and ABP120. Conserved residues are highlighted as black boxed letters and are marked with asterisks. (b) Cartoon diagram of the ABP34 C-domain. Secondary structures are labelled. Conserved residues in (a) are shown as sticks and labelled. The disordered region (257–269) is shown as a dotted line. The overall colour schemes are the same as in Fig. 4 ![[link]](../../../../../../logos/arrows/d_arr.gif) . (c) Cartoon diagram of the F-actin-binding model. The ABP34 monomer was docked into F-actin using the PatchDock server. ABP34 (green) is located on the surface between subdomain 1 and subdomain 2 of an actin monomer (yellow) in F-actin (grey). The conserved strong actin-binding region (216–244) is coloured red and in the enlarged panel residues 216–244 are shown as sticks and the secondary structures in the C-domain are labelled. The three actin-binding sites ABS1, ABS2 and ABS3 are marked and highlighted in magenta. |
![[Figure 7]](tz5079fig7.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
