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Figure 8
Setting up multiple screens with single droplets leads to better identification of hits when compared with setting up single screens with multiple droplets. Here, we compared the hit-identification rates for experiments with one drop at a 1:1 mixing ratio in three screens (blue bars) and with three drops at 2:1, 1:1 and 1:2 mixing ratios in a single screen (green bars) to keep the required protein sample constant. Each screen was only compared with permutations that include itself. Red bars indicate how many hits were missed by both methods.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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