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![[Figure 2]](rr5121fig2mag.jpg)
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Figure 2
(a) Electron-density loss sites as indicated by Dloss in the TRAP–RNA complex crystal by residue/nucleotide type for five doses [sites determined above the 4× average Dloss threshold, calculated over the TRAP–RNA structure for the first difference map: Fobs(d2) − Fobs(d1)]. Cumulative frequencies are normalized to both the total number of non-H atoms per residue/nucleotide and the total number of that residue/nucleotide type present. (b) Average Dloss for each residue/nucleotide type with respect to the DWD (diffraction-weighted dose; Zeldin, Brockhauser et al., 2013  ). 95% confidence intervals (CI) are shown. Only a subset of key TRAP residue types are included. The average Dloss (calculated over the whole TRAP asymmetric unit) is shown at each dose (dashed line). |
![[Figure 2]](rr5121fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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