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![[Figure 1]](cb5087fig1mag.jpg)
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Figure 1
Caprin proteins and structure of the dimerization domain of Caprin-1. (a) Schematic representation of human Caprin-1 and Caprin-2, as well as of Drosophila Caprin (dCaprin). HR1 and HR2, homologous regions 1 and 2. CRD, C1q-related domain. The thin red lines indicate the locations of the RGG boxes. (b) Sequence of the human Caprin-1 dimerization domain aligned with the homologous sequences of Caprin-2 and dCaprin. The secondary structures are indicated above the Caprin-1 sequence. Residues involved in dimerization are indicated with a + sign. (c, d) Structure of the Caprin-1 homodimer rendered in cartoon mode and surface mode, respectively, viewed from three different angles. The two protomers are colored red and blue, respectively. |
![[Figure 1]](cb5087fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
