Figure 4
Model of the ternary complex between hsGcn5L2, different acyl-CoA molecules and peptide. (a) Overall model with hsGn5L2 colored purple, the peptide colored yellow and acetyl-CoA colored green. The catalytic water molecule is depicted as a blue sphere. (b, c, d) Close-up views of the arrangement between the incoming lysine (yellow) and (b) acetyl-CoA (green), (c) propionyl-CoA (cyan) or (d) butyryl-CoA (orange). |