Figure 4
Space-group ambiguity owing to rNCS at (1/4, 1/4, z). The six hlFBPase protomers are represented by spheres at the coordinates of the centre of mass. They are coloured individually and labelled A–F. (a) One half of the molecules related by the fourfold axis (black rod) forms a left-handed fourfold screw axis of three complete turns along the c axis. Successive molecules are translated by c/12. A subset of these molecules is related by a (right-handed) 41 axis (green) connecting symmetry mates. In fact, all like-coloured molecules are related by a 41 axis. (b) The other half of the molecules related by the fourfold axis also forms a left-handed helix, which incorporates a 41 axis (yellow), connecting two different symmetry mates in an alternating pattern. |