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![[Figure 7]](rr5135fig7mag.jpg)
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Figure 7
hlFBPase structure and comparison with related FBPases in the R and T states. (a) Superposition of hlFBPase (subunits coloured yellow, green, red and blue) with R-state porcine liver FBPase in complex with F6P (Choe et al., 1998  ; magenta; PDB entry 1cnq) and with human liver FBPase in the T state (Hebeisen et al., 2011; black; PDB entry 2y5k). (b) View rotated 90° about the horizontal axis to show the close superposition of the R state of apo hlFBPase with the F6P-bound R state of porcine FBPase. (c) The same view as in (b) but comparing the R state of hlFBPase (green/yellow) with the T state of hlFBPase (black). The two states differ by an ∼15° rotation about the C1/C2 axis. |
![[Figure 7]](rr5135fig7.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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