Figure 6
Examples of N-linked glycosylation. Top, plant N-glycans typically show α1–3 core-linked fucose and β1–2 xylose linked to the first mannose sugar. In the figure, a diagram of one of the glycans found in a haem peroxidase from sorghum (PDB entry 5aog; Nnamchi et al., 2016). Middle, a complete, unprocessed high-mannose N-glycan linked to a glycosyl hydrolase enzyme from the fungus Aspergillus fumigatus (PDB entry 5fji; Agirre et al., 2016). Bottom, a sialylated N-glycan linked to an Fc fragment from a human antibody (PDB entry 4byh; Crispin et al. (2013). Human glycans, and also mammalian glycans in general, may display an α1–6 core-linked fucose. All diagrams and legends were generated with Privateer (Agirre, Iglesias-Fernández et al., 2015). For more examples of glycans, refer to the complete overview of N-glycan structures published by Stanley & Cummings (2009). |