Figure 2
Analysis of protein–ligand interactions using CSD data for KIT kinase (PDB entry 4hvs; Zhang et al., 2013). The bound inhibitor is superimposed on the interaction maps. The statistically most likely places one would find hydrogen-bond donors are shown in blue, hydrogen-bond acceptors in red and halogens in green. The maps show that these groups in the modelled ligand match the binding prediction well: it makes plausible interactions. |