view article

Figure 10
YfeA flexibility. The YfeA c-clamp is not entirely rigid. (a) Cartoon representation of YfeA illustrating the positions of the flexible helix and flexible loops relative to site 1 and site 2. (b) Superimposition of crystal forms colored by B factor shows subtle changes in the flexible loops and identifies a lone flexible helix in the carboxy-terminal lobe, annotated the `flexible lobe'. The absence of a flexible helix in the amino-terminal lobe suggests that this lobe is a `rigid lobe'. (c) Orthogonal view of (b) showing the proximity of the flexible helix and loop 223–233 relative to site 1. (d) Enlarged image of (b) at site 1 showing that ligands do not change position across crystal forms.

Journal logoSTRUCTURAL
ISSN: 2059-7983
Follow Acta Cryst. D
Sign up for e-alerts
Follow Acta Cryst. on Twitter
Follow us on facebook
Sign up for RSS feeds