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Figure 1
Comparison of the conventional cooling and HPC workflows. For conventional cooling the crystals are harvested in a loop. The crystal is submerged into a chemical cryocondition and harvested again. Within a few seconds the crystal is placed into a cryovial filled with liquid N2 or placed into a cryostream. For HPC the crystal is harvested once with the capillary of the sample unit. It is now protected by its own mother liquor. Cooling is started and the sample can be taken from the sample dewar to the semi-dry liquid N2 bath. The complete sample holder is formed, which is stored in a cryovial.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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