journal menu
![[Figure 6]](ba5282fig6mag.jpg)
|
|
Figure 6
Likelihood-guided occupancy refinement for PDB entry 2hh6 solved by molecular replacement with CASP7 model T0283TS020_2. (a) The structure 2hh6 (reference copy, ribbon representation, colour ramp from blue to red from the N-terminus to the C-terminus), the N-terminal helix of a symmetry-related copy of 2hh6 (worm representation, colour ramp as for the reference copy) and the result of likelihood-guided occupancy refinement of the placed model showing occupancies per residue ranging from 1 (black) to 0 (purple). The regions where 2hh6 and the model diverge are the regions where the refined occupancies are close to 0 (the model is shown in purple), and conversely where they coincide the refined occupancies are close to 1 (the model is shown in black). The window size for occupancy refinement was five residues, determined by the optimal-target-ΔeLLG. This figure was produced with CCP4mg (McNicholas et al., 2011  ). (b) The difference between the LLGI for the placed model T0283TS020_2 before and after removing five residues centred on each residue along the chain (blue line). The RSCC per residue is shown between the placed model T0283TS020_2 and the `true' map (see text; orange line) and between the placed model T0283TS020_2 and the `model' map (see text; dotted green line). The RSCC of the model to the `true' map is better predicted by the change in LLGI (orange line versus blue line) than by the RSCC to the `model' map (orange line versus dotted green line). |
![[Figure 6]](ba5282fig6.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
access
