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Figure 3
Stereoview of VH, VL, CL and CH1 domains of PDB entry 2hfl superimposed on the corresponding domains of PDB entry 1igj. The r.m.s.d. between optimally aligned 2hfl and 1igj is 1.1 Å over 214 core residues for the variable domains (VL and VH) and 0.95 Å over 198 core residues for the constant domains (CL and CH1), as calculated by SSM (Krissinel & Henrick, 2004BB19) in Coot (Emsley et al., 2010BB15). Breaking the model and target into the four antibody domains further lowered the r.m.s.d. slightly: VL, 0.98 Å (102 residues); VH, 1.1 Å (109 residues); CL, 0.80 Å (103 residues); CH1, 0.95 Å (93 residues). These are the minimum r.m.s.d. values obtainable by molecular replacement.

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ISSN: 2059-7983
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