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Figure 5
MeshBest analysis of the mesh scan of a large, homogeneous, nearly perfect crystal of trypsin. (a) A snaphot of the crystal as mounted on the beamline goniometer; the red rectangular mesh indicates the area and the dimensions of the mesh scan. (b) Cumulative DDV histogram used in multi-pattern diffraction analysis, with the baseline regions determined marked with red circles. The blue line shows the fitted baseline of the cumulative histogram. Its slope indicates the absence of multi-pattern diffraction in the images of the mesh scan. (c) Dendrogram based on HCA of mesh-scan images (see §2.2[link]); the colours correspond to the crystal map in (g). (d) A sample of a raw diffraction image from the mesh scan. (e) A diagram of spots detected by Dozor corresponding to the image in (d). (f) Dozor-score heat map of the mesh scan. (g) A crystal map of the mesh scan generated by MeshBest.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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