Crystal structure of the spliceosomal DEAH-box ATPase Prp2

Schmitt, A.; Hamann, F.; Neumann, P.; Ficner, R.

doi:10.1107/S2059798318006356

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 4
Comparison of the different β-hairpin conformations. (a) All ctPrp2 structures are superposed via their RecA2 domains. The different β-hairpins are presented as cartoon models using the colouring of Fig. 3

(a), while the remaining part of the protein is shown as a surface (nucleotide-free structure only). The OB-fold domain was omitted for clarity. The superposition reveals that the β-hairpin of ctPrp2 can adopt different conformations. (b) Superposition of ctPrp43 structures in different functional states via their RecA2 domains (PDB entries 5d0u, 5lta, 5ltj and 5ltk; Tauchert et al., 2016