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Figure 1
Acoustic droplet ejection (ADE). ADE uses sound energy to transfer variable micro-droplets (e.g. nanolitres or picolitres) of solution (including suspended solids) from a crystallization well, through a short air column (∼1 cm) to data-collection media. Sound-wave energy from the transducer is channelled to the focal point (i.e. the ejection zone), displacing the surface, where a controlled ejection occurs. Droplet size is governed by the wavelength of the sound emitted and this proportionality yields accurate ejected volumes. In this work, an Echo 550 liquid handler was used to harvest protein crystals from two kinds of in situ plates (MiTeGen In Situ-1) onto MiTeGen MicroMeshes.

Journal logoSTRUCTURAL
ISSN: 2059-7983
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