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Figure 2
The four EF-hand calcium-binding loops of calbindin-D28K. Calcium-binding amino acids, water molecules and calcium ions are shown, while the rest of the structure is illustrated by a cartoon representation. Each calcium ion is coordinated with a pentagonal bipyramidal coordination geometry, the bonds for which are represented by a dotted line. The EF1 calcium is coordinated by Asp24, Asp26, Ser28, Tyr30, Glu35 and water, the EF3 calcium by Asp111, Asp113, Ser115, Phe117, Glu119 and Glu122, the EF4 calcium by Asp155, Asn157, Asp159, Lys161, Glu166 and water, and the EF5 calcium by Asp199, Asp201, Asn203, Tyr205, Glu210 and water.

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ISSN: 2059-7983
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