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Figure 3
Comparison of 3TR binding sites in the lateral channel of the E316F (a), V536W (b) and H246W (c) variants superposed onto the complex of CATPO with 3TR. The corresponding 2Fo − Fc electron density, contoured at 0.7 r.m.s.d., is shown for the three cases as a blue mesh. Changes in solvent organization are evident among the structures. Trp246 has two alternate conformations (Fig. 4[link]).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 74| Part 10| October 2018| Pages 979-985
https://doi.org/10.1107/S2059798318010628
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