journal menu
![[Figure 2]](rr5172fig2mag.jpg)
|
|
Figure 2
Crystal structure of EcYiiP. (a) YiiP homodimer from E. coli (PDB entry 3h90) crystallized in a detergent micelle and represented in a lipid bilayer plane. Chain A is coloured according to sequence conservation generated using the ConSurf server, with turquoise through maroon indicating variable through conserved (Ashkenazy et al., 2016  ), on the basis of an alignment of YiiP and human zinc transporters (ZnTs). Chain B is coloured light green. Zn2+ ions are shown as orange spheres at the sites labelled A, B and C. (b) View of the structure from the periplasmic side, showing the bundle of four helices and the bundle of two helices and the salt bridges formed by (Lys77–Asp207)2. The CTDs have been removed for clarity. (c, d, e) Binding sites A, B and C, respectively, with bound Zn2+ (orange spheres) and coordination residues (shown in stick representation and labelled). |
![[Figure 2]](rr5172fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
access
