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Figure 1
Chromatogram showing size-exclusion traces for the Mcl-1–Fab complex and controls. Peaks a (red) and b (blue) correspond to Mcl-1 and Fab, respectively. Volumetric Mcl-1:Fab ratios were 1:4 (peak d, brown) and 1:3 (peak c, green). The shoulder on peak c is indicative of residual Mcl-1 compared with peak d, which suggests a fully reacted mixture. |
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