Figure 4
Comparison of FWER- and FDR-controlling procedures in confidence maps. Confidence maps based on (a) Holm FWER and (b) Benjamini–Yekutieli FDR are compared for a γ-secretase map (EMD-3061). Respective inset enlargements in the interior of the transmembrane domain are shown on the right. (c) Comparison of detected false-positive voxels and false-negative water molecules for a simulated map of 4194 water molecules (taken from PDB entry 6cvm). |