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![[Figure 1]](ag5035fig1mag.jpg)
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Figure 1
Metabolic routes of the L-Hyp isomers T3LHyp and T4LHyp in mammals, bacteria and archaea. T3LHyp and T4LHyp follow two distinct degradation pathways which lead to the formation, for T4LHyp, of α-ketoglutarate in mammals and of pyruvate and glyoxylate in bacteria and, for T3LHyp, of L-proline in mammals, bacteria and archaea. For simplicity, the unstable, dehydration reaction product Δ2-pyrroline-2-carboxylate has been omitted and only the stable Δ1-pyrroline-2-carboxylate (Pyr2C) product is shown. |
![[Figure 1]](ag5035fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
