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Figure 4
Representation of the closed and open conformations of P46. (a) Open structure of P46, surface in magenta, corresponding to PDB entry 6rux, with maltose in the binding site. (b) Closed structure of P46, surface in yellow, corresponding to chain A of PDB entry 6s3t, with xylose in the binding site. (c) Expected hinge movement of greater than 30° between the N- and C-domains in the open (magenta) and closed (yellow) conformations of P46. |