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![[Figure 9]](dw5207fig9mag.jpg)
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Figure 9
(a) Electron density for active-site residues, including the catalytic nucleophile (Nuc) Glu340 and catalytic acid/base (a/b) Glu235, contoured to 2σ (1.0 e Å−3). (b) Selection of modelled residues with difference electron density [green; contoured to 3σ (0.37 e Å−3)] highlighting proton positions. (c)–(f) Modelled residues from domain I of GBA (PDB entry 6tn1) demonstrating atomic resolution (electron density contoured to 3.5σ (1.75 e Å−3). |
![[Figure 9]](dw5207fig9.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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