Figure 3
GLIC crystal structures with the unsaturated C4 carboxylates crotonate and fumarate. Crystal structures of GLIC in complex with (a) crotonate (orange stick representation) and (b) fumarate (dark cyan). Both C4 compounds with a double bond in the trans configuration are present only in the intersubunit site, while the intrasubunit pocket is occupied by a chloride ion (green sphere) in both structures. The 2Fo − Fc density contoured at 2 Å around the ligands is coloured blue and contoured at 1σ. |