Figure 5
Close-up views of antagonist recognition. (a, b, c) Close-up views around the antagonist-bound site with (a) CU-CPT9a (PDB entry 5z14), (b) CU-CPT9b (PDB entry 5wyz) and (c) CU-CPT9c (PDB entry 5z15). The agonists are represented as ball-and-stick models in which C atoms are represented in yellow, O atoms in red, N atoms in blue and chloride ions in green. Hydrogen bonds are shown as black dashed lines and the halogen bond is shown as a magenta dashed line. The chemical structure of each ligand is shown below the close-up view. |