Figure 4
Comparison of original maps (a, d), density-modified maps (b, e) and maps density-modified using automatically generated ensemble models (c, f). (a)–(c) Maps for the human polycystin-2/PKD2 TRP channel at a resolution of 4.2 Å (EMDB EMD-8200 and PDB entry 5k47). (d)–(f) Maps for the human CLC-1 chloride ion channel at a resolution of 3.4 Å (EMDB EMD-7544 and PDB entry 6coy). Differences between maps are noted with arrows and selected residues in the deposited models are labeled. Maps in each set are contoured to enclose equal volumes (Urzhumtsev et al., 2014). |