journal menu
![[Figure 2]](jb5019fig2mag.jpg)
|
|
Figure 2
(a) Sequence alignment of the RING domains of human TRIM69 (UniProt Q86WT6), TRIM5α (UniProt Q9C035), TRIM32 (UniProt Q13049) and TRIM37 (UniProt O94971). The residues involved in coordinating Zn1 and Zn2 are shown in yellow and red, respectively. (b) Crystal structure of the TRIM69 RING domain. Residues that coordinate the two Zn atoms are shown in stick representation. Secondary-structure elements and Zn atoms are annotated. (c) Details of interactions within the four-helix bundle are shown; the RING zinc-finger domains have been removed for clarity. (d) Comparison of the TRIM69 RING domain with those of TRIM5α (red), TRIM32 (green) and TRIM37 (purple). |
![[Figure 2]](jb5019fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
