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Figure 4
Δ1L2M CXCL13 crystal structure. Data-collection and refinement statistics are shown in Table 1[link] and structural features are labeled. Missing residues are shown as dashed lines. (a) Δ1L2M CXCL13 crystallizes in space group P1211 with seven monomers in the asymmetric unit. Each monomer is colored a separate color for clarity. (b) The N-termini of the Δ1L2M CXCL13 monomers mediate interactions that collectively lead to the formation of a five-stranded β-sheet between two monomers. Note that the N-terminus of one monomer is visible, while the labeled C-terminus is that from another monomer. Only two monomers are shown for simplicity. (c) Alignments of all seven monomers in the asymmetric unit demonstrate that the N-terminus and core domain only exhibit minor alterations (see Supplementary Fig. S2 for calculated r.m.s.d. values).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 76| Part 10| October 2020| Pages 1033-1049
https://doi.org/10.1107/S2059798320011687
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