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![[Figure 1]](di5038fig1mag.jpg)
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Figure 1
Cluster outcomes for multi-data set PTP1B. (a) Correlation plot showing relationships between data sets in reciprocal space according to Section 2 ![[link]](../../../../../../logos/arrows/d_arr.gif) for clusters 1–9 in that order. The colour scale ranges from blue (coefficient of 0) through white (coefficient of 0.5) to red (correlation of 1). Alternating dark/light boundaries down the right-hand-side bar are a guide to the cluster boundaries. (b) Similar correlation plot based on Cα differences. (c) Two views of Cα positions for structures from clusters 2 (light blue), 3 (purple) and 6 (pink). (d) Views of 16 of the newly identified ligands, chosen from clusters 1–9 where the data-set number is less than y1000. PanDDA background-corrected event maps are displayed from the pre-clustered analysis in all cases (2σ), as these were often not calculated for maps dropping below the Z threshold in the unpartitioned analysis. Z-maps were available for both analyses in all cases, and so the corresponding map is displayed with positive values in green and negative values in red (±3σ). Electron-density figures were rendered in Coot (Emsley et al., 2010). |
![[Figure 1]](di5038fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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