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Figure 5
Multi-data set BRD1A. (a) Matrix plot showing the relationships between data sets in reciprocal space using the same colour scheme as in Fig. 2[link](a). (b) Matrix plot showing relationships in real space between Cα positions. (c, d) PanDDA maps displayed as in Fig. 2[link]. (c) Tree showing the generation of subclusters from all data sets. Selections for subclusters were chosen through inspection of the SVD plots. A subselection of data sets contributes to each matrix plot, and of these a subset is highlighted in yellow, either denoting the final members of clusters A–H or, if a non-terminal cluster, the subselection displayed in the downstream matrix plots. Clusters A and B were split along reciprocal amplitude differences, and clusters C–H were further split along Cα differences. (d) Newly identified hit from x165. (e) Newly identified hit from x324. (d) and (e) were rendered in Coot (Emsley et al., 2010BB6).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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