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![[Figure 7]](ir5018fig7mag.jpg)
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Figure 7
LAHMA output for Mps1 kinase with PDB entry 5ntt as the query structure. (a) Notable structural features are clearly highlighted: residues 602–606 contact the ligand, residue 686 is phosphorylated, residues 675–677 that are part of the activation loop of Mps1 kinase are found to be phosphorylated in homologs but not in this structure model, and the activation loop is typically disordered in crystal structures of Mps1 kinase. (b) Number of ligand contacts for residue 604. In about half the cases this residue makes one or more ligand contacts. (c) The Ramachandran plot distribution for residue 604 shows two distinct clusters. (d) Phosphorylation of residue 686 is found in a quarter of the structure models. |
![[Figure 7]](ir5018fig7.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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